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Given the flexibility in which you can choose to use and deploy vROps a question that frequently comes out is “is there a best practice?”
While that phrase is getting pretty tired it is still valid if you are just starting a design for a new vROps build or trying to make the best of a bad implementation. Rather than me trying to tell you how you should use vROps in your place of work I would direct you to a very useful PDF VMware have produced vRealize Operations Manager Reference Architecture.
Needless to say this is a tremendously useful resource and should be a port of call for anyone validating their vROps design choices.